Tallying Lysine Acetyltransferases with Chemoproteomic Profiling
نویسنده
چکیده
opal UGA stop codon, whereas in the eukaryotes, it is the ochre UAA stop codon. Viruses reassigned the ochre UAA or amber UAG stop codons. The largest number of recoding events appeared in a sulfidic groundwater sample and in the human oral microbiome. In an artful use of reassignment, it appears that some phages use codon reassignment to hijack the host machinery to begin translate their own stopcodon containing proteins. The phages even bring along the proper stop-suppressing tRNA and release factor for the job. This study indicates the wealth of biology yet to be studied on the Earth and how dogmas are sometimes overturned. Jason G. Underwood, Ph.D.
منابع مشابه
Chemoproteomic Profiling of Lysine Acetyltransferases Highlights an Expanded Landscape of Catalytic Acetylation
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